Seo et al believe that fluoxetine can counteract the contraction of the vas deferens caused by adrenaline, thereby delaying ejaculation. At present, there are many reports that fluoxetine has a significant curative effect for PE. We hope to systematically evaluate the published RCTs of fluoxetine for PE to provide evidence for its clinical use.
by NM Yaacob 2024CONCLUSION: Treatment of PE with either Fluoxetine or Dapoxetine decreases PE symptoms and increases marital satisfaction. 0.001) among DG].
Fluoxetine was the first molecule of a new generation of antidepressants, the Selective Serotonin Re-uptake Inhibitors (SSRIs). Stokes PE, Holtz A. Fluoxetine
Efficacy of fluoxetine in treatment of PE. Fluoxetine is more selective and more potent in retarding ejaculation as compared to TCAs [45]. At a dose of 20 mg daily for 1 week followed by 40 mg daily for ~4 weeks, fluoxetine successfully improved PE in a double-blind placebo controlled study of 17 patients [46].
by E Moudi 2024 Cited by 22Paroxetine is better than fluoxetine, clomipramine and sertraline in the treatment of PE. Fluoxetine is inferior to sertraline, while the
escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil) Examples: pseudoephedrine (Sudafed), phenylephrine (Sudafed PE)
Paroxetine and fluoxetine provide significant efficacy in patients with PE . In 2024 Forster first described the use of fluoxetine as treatment for PE and Waldinger et al. enrolled the first randomized trial assessing paroxetine in PE treatment. Paroxetine treatment results in a 5 to 8-fold increase in IELT.
Efficacy of fluoxetine in treatment of PE. Fluoxetine is more selective and more potent in retarding ejaculation as compared to TCAs [45]. At a dose of 20 mg daily for 1 week followed by 40 mg daily for ~4 weeks, fluoxetine successfully improved PE in a double-blind placebo controlled study of 17 patients [46].
Efficacy of fluoxetine in treatment of PE. Fluoxetine is more selective and more potent in retarding ejaculation as compared to TCAs . At a dose of 20 mg daily for 1 week followed by 40 mg daily for ~4 weeks, fluoxetine successfully improved PE in a double-blind placebo controlled study of 17 patients .
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