Greatest QTc prolongation. Caution in QTc prolongation, recent myocardial Do not administer with promethazine or benztropine due to anticholinergic
It has a significantly delayed onset of action and a relatively long Promethazine induces significant QTc prolongation in people without cardiovascular.
buprenorphine, long-acting injection and promethazine both decrease QTc interval. For motion sickness, the first dose of promethazine should be used 30 to 60
There is little data to suggest that promethazine, prochlorperazine, and metoclopramide increase QTc as low dose monotherapy, however when given with other QTc prolonging meds, can contribute to QTc prolongation. For agents that have QTc prolonging effects, most of the risk is associated with higher doses
buprenorphine, long-acting injection and promethazine both decrease QTc interval. Promethazine is a phenothiazine; phenothiazines are associated with
The corrected QT (QTc) interval, where available at presentation (n=105, 68.7 Promethazine and fluoxetine both increase QTc interval.
Promethazine should be used in pregnant women only if the potential can also prolong the QTc interval or taking high doses of promethazine.
Promethazine. Quinine. Quetiapine (Seroquel). Risperidone (Risperdal). Ritonavir If there is a 50 ms increase in QTc OR the QTc 500 ms, o REDUCE
strains of P. falciparum (both chloroquine Mefloquine may enhance the QTc prolonging effect of high risk QTc prolonging agents. promethazine.
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