The co-expression of endocrine receptors and HER2, albeit associated with resistance to hormonal and anti-HER2 therapy, resulting in worse prognosis, creates an opportunity of combination treatment, consisting of anti-HER2 drugs and ET, in particular when dual HER2-blockade is used.
Drugs that specifically treat HER2 breast cancer are called anti-HER2 drugs. Designed to only attack the cancer cells, they include HER2 antibodies, HER2
HER2-directed therapyMost women with HER2-positive breast cancer will receive one or more chemotherapy drugs plus trastuzumab, the anti-HER2
HER2-directed therapyMost women with HER2-positive breast cancer will receive one or more chemotherapy drugs plus trastuzumab, the anti-HER2
An analysis of data on non–small cell lung cancer (NSCLC) patients with HER2 mutations has raised hopes that anti-HER2 drugs used to treat HER2-
Exploring HER2 Targeting: Transforming Treatment for Metastatic and Locally Advanced HER2 Cancers. The emergence of HER2-targeted antibody-drug conjugates
HER2 mutations, have proven to be extremely challenging to drug. Lung cancer patients with HER2 mutations treated with chemotherapy and HER2-targeted drugs:
All breast cancers are tested for HER2 status to help guide treatment. If a tumor is HER2-positive, the HER2-targeted therapy drug trastuzumab (Herceptin) is included in the chemotherapy regimen. Sometimes other drugs that target HER2 are used. Learn more about trastuzumab and other HER2-targeted therapies for early breast cancer.
All breast cancers are tested for HER2 status to help guide treatment. If a tumor is HER2-positive, the HER2-targeted therapy drug trastuzumab (Herceptin) is
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