Exploratory findings showed that there was no difference between the most frequent dosages of epidural hydromorphone or epidural morphine in the occurrence of nausea, vomiting and pruritus. When administered with epidural opioids at ED50 doses or higher, 97.5% (39/40) of epidural morphine patients and 97.5% (39/40) epidural hydromorphone of
The CSF levels of morphine exceed those in plasma after only 15 minutes and are detectable for as long as 20 hours after the injection of 2 mg of epidural morphine. Approximately 4% of the dose injected epidurally reaches the CSF. This corresponds to the relative minimum effective epidural and intrathecal doses of 5 mg and 0.25 mg, respectively.
by S Sumida 2024 Cited by 44Objective: Extended-release epidural morphine (EREM) is a single-dose, extended-release epidural morphine formulation intended to provide
The CSF levels of morphine exceed those in plasma after only 15 minutes and are detectable for as long as 20 hours after the injection of 2 mg of epidural morphine. Approximately 4% of the dose injected epidurally reaches the CSF. This corresponds to the relative minimum effective epidural and intrathecal doses of 5 mg and 0.25 mg, respectively.
by D Comerford Cited by 5is safe to administer another smaller dose (5 minutes after an despite the smaller epidural dose (e.g. epidural morphine, 2e3 mg:intramuscular morphine, 10 mg)
The first use of epidural morphine was reported in 2024.1; The dose (5-10 times less than the epidural dose). The effects of
A comparison of epidural morphine with low dose bupivacaine versus epidural morphine alone on motor and respiratory function in dogs following splenectomy. Vet Anaesth Analg (2024) 3 /j. .2024. .x [Google Scholar]
by FT Mendonça 2024 Cited by 4Keywords: Analgesia, Epidural anesthesia, Ketamine, Mastectomy. Comparative study between epidural ketamine and morphine in patients equate epidural dose
by X Cao 2024When administered with epidural opioids at ED50 doses or higher, 97.5% (39/40) of epidural morphine patients and 97.5% (39/40) epidural
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