Most symptoms are caused by the underlying disease or condition that is causing the metabolic acidosis. Metabolic acidosis itself most often causes rapid breathing. Acting confused or very tired may also occur. Severe metabolic acidosis can lead to shock or death. In some situations, metabolic acidosis can be a mild, ongoing (chronic) condition.
Causes Metabolic acidosis Renal tubular acidosis Respiratory acidosis Diet-induced acidosis Drug-induced acidosis.
Treatment for metabolic acidosis depends on the cause. Some causes are temporary and the acidosis will go away without treatment. Metabolic acidosis due to alcohol or drug poisoning is treated
Metabolic acidosis is a clinical disturbance defined by a pH less than 7.35 and a low HCO3 level. The anion gap helps determine the cause of the metabolic acidosis. An elevated anion gap metabolic acidosis can be caused by salicylate toxicity, diabetic ketoacidosis, and uremia (MUDPILES).
Metabolic acidosis is common in acutely unwell patients and indicates an underlying pathophysiological disturbance. Treatment should be primarily directed at the underlying condition, not the acidosis. Thus, a key element of managing metabolic acidosis is determining the underlying cause. In most cases, metabolic acidosis is caused by increased plasma concentrations of pathologic anions and
It is not always clear whether these conditions cause metabolic acidosis, or whether acidosis causes these conditions. Drug-induced acidosis. Some prescription medications can increase acidity
It is not always clear whether these conditions cause metabolic acidosis, or whether acidosis causes these conditions. Drug-induced acidosis. Some prescription medications can increase acidity
Many other medications and poisons can cause acidosis. Metabolic acidosis (lactic acidosis) and in poorly controlled type 1 diabetes mellitus (
hyperkalemia and metabolic acidosis, while carbonic anhydrase inhibitors such as acetazolamide can cause hypokalemia and metabolic acidosis.
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