Prednisone and Blood Sugar Levels. One of the known side effects of prednisone is its potential to increase blood sugar levels. Prednisone can stimulate glucose production in the liver while decreasing the effectiveness of insulin, the hormone responsible for regulating blood sugar. This combination can lead to higher blood sugar levels
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corticosteroids (prednisone/prednisolone). Prednisone (prednisolone) is. blood sugar, and the blood sugar increases. This is steroid-induced diabetes
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