Acyclovir and kidney failure

An important side effect of acyclovir is acute renal failure. Acyclovir-induced renal failure may be caused by intratubular deposition of acyclovir crystals in the kidney due to the low solubility of acyclovir in urine. The risk of deposition of acyclovir crystals in the kidney can be avoided by slow drug infusion over 1 to 2 h and volume

by P Arriaga 2024Keywords: acute kidney failure, acyclovir nephrotoxicity, crystal nephropathy. crystals, but, without polarizing light microscopy, they can be missed.

Acyclovir Adjust dose in patients with renal failure. Acyclovir may precipitate in kidneys if the solution is infused too quickly ( 1 hr) or is too

Acyclovir Adjust dose in patients with renal failure. Acyclovir may precipitate in kidneys if the solution is infused too quickly ( 1 hr) or is too

Acyclovir is metabolized in the liver and excreted from the body through the kidneys. In some cats, especially those with pre-existing kidney or liver diseases, Acyclovir can accumulate in the body and cause toxicity. Acyclovir toxicity manifests as renal failure and hepatotoxicity, which can be irreversible if not treated timely.

A well-known side effect of acyclovir is nephrotoxicity. The most common manifestation of acyclovir-induced kidney failure is an obstructive nephropathy caused by the intratubular precipitation of crystals and characterised by haematuria, pyuria and crystalluria.

by P Arriaga 2024Keywords: acute kidney failure, acyclovir nephrotoxicity, crystal nephropathy. Renal metabolism accounts for % of acyclovir clearance (unchanged

By definition acute kidney failure is temporary. Otherwise it is chronic kidney failure. In the case of acyclovir induced injury, it is reversible in most cases, though not all depending on various factors, and predicting the outcome of a specific case would be quite hazardous.

Do not use medications containing Acyclovir while using Valacyclovir. What are the possible side effects of Valacyclovir? Kidney failure and nervous system