DOPAMINE HYDROCHLORIDE AND 5% DEXTROSE INJECTION, USP Page 6 of 22 IMPORTANT: Antidote for Peripheral Ischemia No clinical experience exists in which phentolamine has been administered as an antidote for peripheral ischemia due to dopamine. However, the following is suggested based on experience with other catecholamines.
Hyaluronidase as an antidote to extravasation of Vinca alkaloids Reversal of dopamine extravasation injury with topical nitroglycerin ointment.
Phentolamine is the local antidote for peripheral ischemia resulting from extravasation of dopamine. Phentolamine should be given as
Antidotes Name of Drug Antidote 1. Acetaminophen Acetylcycteine 2 Dopamine Phentolamie 32. Fluorouracil Leucoverin calcium 33
Study Tips and Notes: One antidote option for dopamine is phentolamine, which blocks alpha receptors. Phentolamine will counteract the effect of
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