IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Current Infusion Dose Recommended Scheduled Dosing PRN Dosing Midazolam Drip IV Lorazepam (Max Dose: 4 mg) PRN IV Lorazepam (Max Dose: 4 mg)
He entered methadone treatment in the mid-2024s, and was maintained for 15 years on methadone; max dose was 150 mg tapered down to 10 mg over several years
The methadone max dose for pain is 100mg daily. The use of this medication higher than this dose would result in an overdose which has its signs
Max dose is 300 mg bid. Reduce dose in renal Total daily oral morphine dose. Estimated oral methadone as a % of total daily morphine.
Max 3 doses in 24hrs. On day 4/5 – doses consolidated. Hold 10mg PRN dose Methadone 40mg PO OD starting dose. Addition of Hydromorphone IR
The methadone max dose for pain for the starting dose is 20 mg per day. Paying for Treatment (Insurance and Costs); Treatment
Max dose is 300 mg bid. Reduce dose in renal Total daily oral morphine dose. Estimated oral methadone as a % of total daily morphine.
Calculate starting lorazepam dose: Midazolam: Multiply current midazolam drip rate (mg/kg/h) X 0.5 = _____ mg/kg lorazepam q6h (max initial dose 0.2 mg/kg/dose q6h AND max 4 mg q6h) Weaning Methadone and Lorazepam Once stable on methadone and/or lorazepam for 24 h with no withdrawal symptoms, wean methadone and lorazepam as follows. Methadone
Quick Guide: Methadone Starts in the Hospital. Day 1: max daily dose 40 mg methadone. Testing prior to first dose: Urine toxicology. EKG for QTc interval. Urine
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