Metabolizing drugs

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Actual: Drug metabolism studies provide the opportunity to enhance metabolic properties of new drugs. The overall aims of the drug metabolism studies are to (1.)
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Drug metabolism Cytochrome P450 Conjugation Drug transporters Liver metabolism Phase I, II, and III metabolism enzyme KEY POINTS Drug metabolism typically results in the formation of a more hydrophilic compound that is readily excreted by the liver, kidney, and/or gut. Drug metabolism involves chemical biotransformation of drug molecules by

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Metabolism: Focus on the different metabolic pathways of drugs and factors affecting drug metabolism. DaVinci Medical Academy : DMA, Chennai

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Polymorphic drug-metabolizing enzymes (DMEs) are responsible for the metabolism of the majority of psychotropic drugs. By explaining a large portion of variability in individual drug metabolism

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7.4 Drugs that Interfere with Hemostasis (e.g, NSAIDs, Aspirin, and Warfarin) 7.5 Lorazepam. 7.6 Temazepam. 7.7 Drugs that Affect Gastric Acidity 7.8 . Drugs Metabolized by CYP1A2 7.9 . Drugs Metabolized by CYP2D6 7.10 Drugs Metabolized by CYP2C9 . 7.11 Drugs Metabolized by CYP3A 7.12 Drugs Metabolized by CYP2C19 . 7.13 Monoamine Oxidase

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7.4 Drugs that Interfere with Hemostasis (e.g, NSAIDs, Aspirin, and Warfarin) 7.5 Lorazepam. 7.6 Temazepam. 7.7 Drugs that Affect Gastric Acidity 7.8 . Drugs Metabolized by CYP1A2 7.9 . Drugs Metabolized by CYP2D6 7.10 Drugs Metabolized by CYP2C9 . 7.11 Drugs Metabolized by CYP3A 7.12 Drugs Metabolized by CYP2C19 . 7.13 Monoamine Oxidase

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Drug metabolism also involves a phenomenon called first-pass metabolism. This occurs when a drug is metabolized at a specific location in the

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Metabolism of xenobiotics by cytochrome P450; : Drug metabolism - cytochrome P450; : Drug metabolism - other enzymes. 1.12 Chemical structure

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7.4 Drugs that Interfere with Hemostasis (e.g, NSAIDs, Aspirin, and Warfarin) 7.5 Lorazepam. 7.6 Temazepam. 7.7 Drugs that Affect Gastric Acidity 7.8 . Drugs Metabolized by CYP1A2 7.9 . Drugs Metabolized by CYP2D6 7.10 Drugs Metabolized by CYP2C9 . 7.11 Drugs Metabolized by CYP3A 7.12 Drugs Metabolized by CYP2C19 . 7.13 Monoamine Oxidase

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Drug metabolism Cytochrome P450 Conjugation Drug transporters Liver metabolism Phase I, II, and III metabolism enzyme KEY POINTS Drug metabolism typically results in the formation of a more hydrophilic compound that is readily excreted by the liver, kidney, and/or gut. Drug metabolism involves chemical biotransformation of drug molecules by

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