Note: Follow up IV therapy with oral acyclovir or valacyclovir maintenance therapy. Maintenance treatment: Begin after 10- to 14-day course of IV acyclovir: Oral: 20 mg/kg/dose 4 times daily for 4 to 6 weeks. HSV prophylaxis; immunocompromised hosts, seropositive: Hematopoietic stem cell transplant (HSCT) in seropositive recipient (Tomblyn 2024):
Maintenance treatment (alternative to valacyclovir): Begin after 10- to 14-day course of IV acyclovir: Oral: 20 mg/kg/dose 4 times daily for 4 to 6 weeks.
Note: Follow up IV therapy with oral acyclovir or valacyclovir maintenance therapy. Maintenance treatment: Begin after 10- to 14-day course of IV acyclovir: Oral: 20 mg/kg/dose 4 times daily for 4 to 6 weeks. HSV prophylaxis; immunocompromised hosts, seropositive: Hematopoietic stem cell transplant (HSCT) in seropositive recipient (Tomblyn 2024):
by MA Lemak 2024 Cited by 103Four patients were treated with a maintenance dose of acyclovir for periods ranging from 10 to 26 months; there were no significant side effects from the
Note: Follow up IV therapy with oral acyclovir or valacyclovir maintenance therapy. Maintenance treatment: Begin after 10- to 14-day course of IV acyclovir: Oral: 20 mg/kg/dose 4 times daily for 4 to 6 weeks. HSV prophylaxis; immunocompromised hosts, seropositive: Hematopoietic stem cell transplant (HSCT) in seropositive recipient (Tomblyn 2024):
Recommended methods for maintenance dosing adjustments are dose reductions, lengthening the dosing interval, or both. Acyclovir (oral) 200 to 800 mg every 4 to 12 hours: 100%: 100%: 200 mg
acyclovir) (2× maintenance dose) twice a day (BID) will be employed, followed by 15 weeks of maintenance dose of antiviral drug (famciclovir or acyclovir) BID.
Because of the risk of renal toxicity, patients on intravenous acyclovir should receive maintenance IV fluids and have Safety and efficacy of high-dose
Initial treatment: IV: 10 to 15 mg/kg/dose every 8 hours for 10 to 14 days. Note: Follow up IV therapy with oral acyclovir or valacyclovir maintenance therapy. Maintenance treatment: Begin after 10- to 14-day course of IV acyclovir: Oral: 20 mg/kg/dose 4 times daily for 4 to 6 weeks. HSV prophylaxis; immunocompromised hosts, seropositive:
Comments