Treatment of excessive sleepiness associated with narcolepsy with or without cataplexy, in adults (licensed indication). Treatment of fatigue in patients with
narcolepsy symptoms and was noninferior for the treatment of EDS in Type 1 narcolepsy. 5,8 Both drugs were equally effective treatments for Type 2 narcolepsy.
Modafinil is indicated in adults for the treatment of excessive sleepiness associated with narcolepsy with or without cataplexy.
Narcolepsy type 2 is defined as narcolepsy without cataplexy. The Food and Drug Administration (FDA) has approved three drugs specifically for the treatment
Limit prescribing of modafinil to the treatment of excessive sleepiness associated with narcolepsy in adults, with or without cataplexy (the
Those who experience narcolepsy with EDS but without cataplexy are diagnosed with type 2 narcolepsy. There currently is no cure for narcolepsy, but with medication and behavioral changes, the condition can be managed. In the past, people living with narcolepsy have had limited treatment options.
Pitolisant is likely to be used both as first- or second-line treatment for narcolepsy with or without cataplexy and as add-on treatment with other narcolepsy medications. Potential DDIs with antidepressants (which may be used off-label for treatment of narcolepsy) that are metabolised by or affect the activity of CYP enzymes should be considered.
treatment of narcolepsy in patients without cataplexy. For patients Antidepressant drugs for narcolepsy. Cochrane Database of.
by VC Abad 2024 Cited by 113medications used to treat narcolepsy symptoms along with Approved in EU for treatment of narcolepsy with and without cataplexy; improves EDS, attention;
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