There is evidence that co-administration of methotrexate and omeprazole prolongs the elimination of methotrexate via kidneys. Co-administration of proton
methotrexate. Monitor/Modify Tx. omeprazole methotrexate. consider stopping proton pump inhibitor during high-dose methotrexate: combo may incr. methotrexate
methotrexate in high-dose methotrexate therapy Inhibitory potencies of omeprazole, lansoprazole, rabeprazole and pantoprazole on MTX
Methotrexate. Omeprazole may increase the effects of methotrexate. Your doctor may adjust your dose depending on the levels of methotrexate in your body. Diazepam.
Omeprazole and Methotrexate. Omeprazole can increase the blood levels and side effects of methotrexate. Concomitant use of the two drugs may elevate and prolong serum concentrations of methotrexate and its metabolite hydroxymethotrexate, possibly leading to methotrexate toxicities. Omeprazole and Clopidogrel (Plavix)
Methotrexate 2.5 mg Tablets (methotrexate) must only be taken once a week. There is evidence that co-administration of methotrexate and omeprazole prolongs
Omeprazole taken with clopidogrel can lower the activity of clopidogrel, so avoid taking these drugs together. Taking omeprazole with methotrexate may result in high levels of methotrexate or methotrexate toxicity. Your doctor may temporarily stop omeprazole treatment if you are taking a high dose of methotrexate.
Methotrexate, The serum concentration of Methotrexate can be increased when it is combined with Omeprazole. Methsuximide, The metabolism of Methsuximide can
PRILOSEC (omeprazole) Delayed-Release Capsules and PRILOSEC. (omeprazole Methotrexate: PRILOSEC may increase serum levels of methotrexate. (7.7).
Hence Omeprazole being a much more expensive drug than it is now.....