Phenytoin vs fosphenytoin

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Actual: Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in
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Doses of fosphenytoin are always expressed in terms of milligrams of phenytoin sodium equivalents (mg PE): fosphenytoin 1 mg PE is equivalent to 1 mg phenytoin sodium and therefore no adjustment should be made when substituting fosphenytoin for phenytoin sodium or vice versa; Storage requirements:

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Fosphenytoin can also be substituted, for short-term use, for oral phenytoin. Fosphenytoin should be used only when oral phenytoin administration is not

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by M Madhiyazhagan 2024Department comparing phenytoin versus fosphenytoin protocol over of seizure with phenytoin compared to the fosphenytoin arm (17.7% vs.

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Phenytoin vs Fosphenytoin The efficacy of phenytoin and fosphenytoin for time to seizure cessation are comparable, however there are theoretical reasons why fosphenytoin might be preferred: Phenytoin and fosphenytoin have sodium channel blockade effects, which is similar to the mechanism of action of certain toxidromes such as TCA and cocaine

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Comparing Fosphenytoin vs Phenytoin ; Be the first to share your experience with this drug. Phenytoin has an average rating of 7.5 out of 10 from a total of 112

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Phenytoin and fosphenytoin are the same active medication. For these reasons fosphenytoin is the preferred second line agent for treatment of

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vs 11% of IM placebo-treated patients hypoalbuminemia, fosphenytoin clearance to phenytoin may be increased without a similar increase in phenytoin clearance.

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vs 0.61 ± 0.02 L/kg) in patients with Fosphenytoin and phenytoin in patients with status epilepticus: improved tolerability versus increased costs.

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Dose equivalence and conversion for fosphenytoin sodium Doses are expressed as phenytoin sodium equivalent (PE); fosphenytoin sodium 1.5 mg ≡ phenytoin sodium

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