Lqts drugs

Long QT syndrome (LQTS) is a cardiovascular disorder resulting from improper functioning of cardiac ion channels. The malfunction can be attributed to either genetic mutation, as seen with congenital LQTS, or from exposure to drugs or metabolic abnormalities, as seen with acquired LQTS in patients who carry the LQTS gene.

An important consideration is that patients who are diagnosed with acquired LQTS may in fact have underlying congenital LQTS that is unmasked with QT-prolonging drugs. 43 In an international cohort of patients with apparent acquired LQTS, about one-fourth of patients harbored a pathogenic LQTS gene variant. 44 Hence, patients with

LQTS may be either congenital or acquired. Acquired LQTS usually results from drug therapy, although other factors such as hypokalemia, hypomagnesemia, and bradycardia can increase the risk of drug-induced LQTS. The clinical manifestations, diagnosis, and management of acquired LQTS will be reviewed here.

Drug-induced LQTS is the most common cause of a-LQTS; as a matter of fact, a survey by Schwartz et al [3] of 670 patients in the International LQTS Registry revealed that anesthesia can trigger LQTS.

Although there is no cure for LQTS, we can treat the disorder to prevent fainting and dangerous arrhythmias. This form of acquired LQTS is called drug-induced

Long QT syndrome (LQTS) whereas treatment of the underlying cause (drug, electrolyte. abnormality, etc.) is the first-line therapy for . acquired LQTS. Etiology. A .

All patients with LQTS should avoid medications contra-indicated in LQTS. A list of these drugs can be found on the net under 'LQT drugs' Those with a long QT

Drugs are the most common cause of acquired Long QT syndrome. Cardiac disorders are also a frequent cause of acquired LQTS. Acquired, drug-induced LQTS is

Long QT syndrome (LQTS) is a disorder of cardiac repolarization drugs to avoid in congenital LQTS. This site is updated regularly with free