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naltrexone plus active gabapentin (N=50), naltrexone plus placebo gabapentin (N=50), or placebo naltrexone and placebo gabapentin (N=50), using a double dummy placebo-controlled medication design. Naltrexone or its matching placebo was given as 25 mg for 2 days and then 50 mg/day for up to 16 weeks. Gabapentin (300-mg cap-
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Naltrexone is commercially available as 50 mg capsules, and the total daily dose for OUD treatment is 50 mg to 100 mg. Low-dose naltrexone (LDN) refers to doses
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