Simvastatin and amlodipine
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Coadministration of simvastatin with amlodipine increases the systemic exposure of simvastatin; Limit simvastatin dose in patients on amlodipine 20 mg/day
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the drug-drug interaction between amlodipine and simvastatin except simvastatin or patients receiving simvastatin without amlodipine
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the drug-drug interaction between amlodipine and simvastatin except simvastatin or patients receiving simvastatin without amlodipine
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2. Impact of Amlodipine on Other Drugs Simvastatin: Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily.
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Coadministration of simvastatin with amlodipine increases the systemic exposure of simvastatin; Limit simvastatin dose in patients on amlodipine 20 mg/day
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However, there is a drug interaction between simvastatin and amlodipine. Amlodipine can increase the concentration of simvastatin which
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The current MHRA recommendations reflect updates to the SmPCs for amlodipine and simvastatin. Istin (amlodipine) Co-administration of multiple doses of 10mg of amlodipine with 80mg simvastatin resulted in a 77% increase in exposure to simvastatin compared to simvastatin alone. Limit the dose of simvastatin to 20mg daily in patients on
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Amlodipine and Simvastatin Amlodipine and simvastatin are used to treat different things (amlodipine- high blood pressure and simvastatin high cholesterol) and sometimes prescribed together. Taking them together may increase the amount of simvastatin in the blood.
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by YT Zhou 2024 Cited by 73lacidipine–simvastatin, amlodipine–simvastatin, benidipine-simvastatin, azelnidipine– amlodipine–simvastatin interaction information. Since a dose reduction
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