Rasburicase vs allopurinol
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○ Restrict potassium intake (avoid IV and PO potassium safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone -
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Tumor Lysis Syndrome: Allopurinol vs Rasburicase Nephpearls IMpearls @edgarvlermamd.
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vs 4% respectively), however a difference in laboratory. TLS incidence was observed between rasburicase and allopurinol groups (21% vs 41%.
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rasburicase in the incidence of tumour lysis syndrome and patient-important outcomes. Compared to allopurinol, rasburicase may reduce the incidence of
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by G Lupușoru 2024 Cited by 30evaluated the uric acid lowering effect of rasburicase versus rasburicase followed by allopurinol administration, versus allopurinol. The
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Tumor Lysis Syndrome: Allopurinol vs Rasburicase Nephpearls IMpearls @edgarvlermamd.
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Mechanism of action: rasburicase and allopurinol. Depicted is the pathway of purine catabolism. Rasburicase is a recombinant form of urate
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Treatment with rasburicase has the advantage over allopurinol of not leading to accumulation of Xanthine. Only Rasburicase can act on uric acid
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safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - results of a multicenter phase III study. Journal of
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