Morphine metabolism

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Actual: Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4. Metabolism. Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6
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Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4. Metabolism. Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6

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Codeine: Metabolizes to Hydrocodone and morphine Heroin: Metabolizes to 6-MAM and then to Morphine Morphine and Hydrocodone: metabolize to Hydromorphone.

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Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4. Metabolism. Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6

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Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4. Metabolism. Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6

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Codeine is metabolised in the liver to the active compounds morphine and morphine-6-glucuronide. Codeine metabolism. Metabolism of codeine to

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codeine is metabolized to morphine and small quantities to hydrocodone, these drugs may be found in the urine. Also, morphine may metabolize to produce a

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morphine remains detectable in urine is crucial for both clinical and forensic purposes. Morphine Metabolism and Excretion. Morphine is rapidly metabolized in

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Expected limits of morphine and hydromorphone (as a result of morphine metabolism) concentrations in the urine were established. Part II of this study used the metabolic ratio (hydromorphone-morphine) to determine the inter-patient and intra-patient variability in morphine metabolism to hydromorphone. Metabolic ratio values varied over a large

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effects of morphine morphine/codeine (opiates). ◦ Heroin metabolizes into codeine, codeine metabolizes into morphine. ◦ Relatively high false positive rate.

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