Chloroprocaine spinal dose

comparing chloroprocaine with a low dose of bupivacaine (10mg or less) for spinal anaesthesia. Data from four studies with 109 patients

Before the release of lidocaine, chloroprocaine was used for spinal anesthesia in the 80-mg to 100-mg dose range. 12 With the intent of using spinal chloroprocaine for short outpatient procedures, a recent volunteer study has shown that chloroprocaine has a predictable dose-response between mg and is seemingly devoid of TNS. 13

Since its approval for use in spinal anesthesia in Europe in 2024, chloroprocaine has seen a resurgence. Recent studies have investigated the safety and efficacy of preservative-free chloroprocaine for use in spinal anesthesia, but few provide the incidence of adverse events such as urinary retention and transient neurologic symptoms.

Two RCTs14,19 examined different doses of chloroprocaine. Both found doses of 40 mg resulted in faster resolution of spinal block. One study19

by Z Jafari 2024Intervention. Chloroprocaine (any dose) ; Comparator. Q1 and Q2: Alternative anesthetic drugs used for spinal or epidural local anesthesia (e.g, bupivacaine

by AT Pellegrino 2024Pellegrino, Alejandro Turi. 2-chloroprocaine versus low-dose bupivacaine spinal anesthesia : a systematic review and meta-analysis.

by MB Breebaart 2024 Cited by 4A single dose of IV dexmedetomidine did not prolong sensory block with 40 mg of spinal chloroprocaine. The number of low sensory blocks was

Spinal 2-Chloroprocaine: A Comparison with Small-Dose Bupivacaine in Volunteers. Journal: Anesthesia

Bupivacaine, ropivacaine, mepivacaine, 2-chloroprocaine are commonly used LA for spinal anesthesia. Epidural anesthesia most frequently relies