CBD (cannabidiol) is a non-euphoric component of the cannabis plant and is widely used for a variety of health benefits. There is a lack of data available regarding whether or not CBD interacts Zoloft (sertraline). There is theoretical interaction between CBD and Zoloft based on how CBD can inhibit CYP metabolizing enzymes.
CBD absolutely works differently when I am on Zoloft. I used to take high-dose CBD edibles. Off Zoloft, CBD gives me great anti-inflammatory effects. On Zoloft CBD gives me rebound depression the next morning, often with suicidal ideation. It lasts 1-2 days. THC by itself does not cause this so I switched.
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CBD (cannabidiol) is a non-euphoric component of the cannabis plant and is widely used for a variety of health benefits. There is a lack of data available regarding whether or not CBD interacts Zoloft (sertraline). There is theoretical interaction between CBD and Zoloft based on how CBD can inhibit CYP metabolizing enzymes.
CBD (cannabidiol) is a non-euphoric component of the cannabis plant and is widely used for a variety of health benefits. There is a lack of data available regarding whether or not CBD interacts Zoloft (sertraline). There is theoretical interaction between CBD and Zoloft based on how CBD can inhibit CYP metabolizing enzymes.
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After trouble with Geodon, and being prescribed Zoloft solo, my wife is currently extremely stable on Zoloft as the anti-depressant and Lamictal as the stabilizer after tweaking the dosages and sticking with Pfizer's brand rather than generic for the Zoloft. Not perfect, energy draining side-effects, but very, very stable. From outside you *may* see 'moody' or 'a bit odd' but not 'nuts'. She's held a highly technical office job for 11 years and been with me for 10, the first four years were untreated and she self-contained in public but let loose in private. Lithium would be fantastic if not for the necessary periodic blood tests because, as luck would have it -- needles trip her trigger for a panic attack which sends her into a bipolar (II) episode.
Take care, James. For every one of us who comments, there's a legion of lurkers thinking similar thoughts. You're held in the highest esteem.