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Author: Admin | 2025-04-28
Extracted from ashwagandha leaves that control the spread of cancer to other organs. Its leaves have found to be very effective in the treatment of breast cancer. Therefore, the mechanisms through which, ashwagandha helps in the prevention and treatment of cancer include – immunomodulator, antioxidant, anti-stressor, anabolic effect, reducing fatigue levels and improving the overall resistance of the body. (15, 16)Liver DiseasesExcess alcohol intake or certain toxic drugs may cause damage to the liver and may interfere with its normal functioning. Toxic drugs cause generation of reactive oxygen species that cause damage to the liver cells. If not treated, it may further lead to liver necrosis (death of tissue). In such a condition, the levels of liver marker enzymes increase in the blood. Research has found that ashwagandha root extracts are cheap, easily available and relatively safe for the treatment of liver diseases. It prevents liver damage by restoring the normal structure of liver cells and by reducing the blood level of liver enzymes. Such a drop is a clear indicator that ashwagandha reduces the damage caused to the liver.Production of toxins and free radical are the key players in liver damage. With an increase in the generation of reactive oxygen species, the amount of antioxidant enzymes decreases. Treatment with ashwagandha improved the antioxidant status by increasing the antioxidant enzymes such as catalase, superoxide dismutase, and reduced glutathione. Such strong antioxidant properties indicate that ashwagandha plays an important role in preventing the liver against the harmful effects. (17, 18, 19)Peptic UlcersThe main cause of ulcer is H. pylori infection or an imbalance between causative and protective factors. Drugs such as aspirin, excess alcohol intake and smoking increase the production of gastric acid and lead to the formation of gastric ulcers.Research had found that ashwagandha roots in case of alcohol-induced ulcers reduced the number of ulcers, further incidence of ulcers and increased the factors that inhibit the formation of gastric ulcers. Furthermore, the effects of ashwagandha roots were similar to that of standard drugs used in the treatment of gastric ulcers. Such anti-ulcerogenic property of ashwagandha is attributed to the presence of flavonoids and antioxidants in it. Oxidative stress and excess of free radicals play a causative role in the development of gastric ulcers. NSAIDs, alcohol and smoking increase the burden of free radicals that cause damage to the inner lining of the stomach. Ashwagandha, a source of antioxidant works by scavenging the free radicals. Thus, the gastro-protective role is due to the presence of antioxidants and flavonoids in ashwagandha roots. (20)InfectionsResearch has found that ashwagandha root as well as leaf extract possess anti-bacterial properties against Salmonella Typhimurium. Treatment with ashwagandha reduced the bacterial load in different vital organs and increased the survival rate of subjects with such infection. Different parts of ashwagandha such as roots, stems, fruits and leaves possess strong anti-microbial property. This property was attributed to the presence of flavonoids in free and bound form in different parts of ashwagandha.It was further noted that ashwagandha had antimicrobial activity
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