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Author: Admin | 2025-04-28
Your treatment plan with your psychiatrist, tell them about all over-the-counter medications, prescription drugs, and supplements that you take so they can ensure that Lexapro or Cymbalta is safe for you to take. Which one is better? One drug is not inherently “better” than the other. Some studies have found Lexapro to be more effective in the treatment of major depressive disorder compared to Cymbalta. Additionally, research shows that Lexapro is generally better tolerated than Cymbalta, meaning it causes fewer intolerable side effects. However, this doesn’t mean that the same will hold true for you since everyone is different, and individual responses to medications vary — regardless of clinical trials and studies. While Lexapro might be more effective and cause fewer side effects for one person, Cymbalta might be more effective and tolerable for another. It’s important to work with an experienced, qualified psychiatrist to receive a diagnosis and determine the best course of treatment for you. Remember to be patient. These drugs don’t work immediately, and it can take several weeks to notice a significant difference in your symptoms. Not to mention, it can take some trial and error to determine which prescription medication or combination of medications is most effective for you. Your psychiatrist will be your guide in helping you figure out what will help you feel better. If you’re looking for a psychiatrist, consider Talkiatry. We’re a national psychiatry practice that treats mental health conditions ranging from anxiety to depression and everything in between. We provide virtual, in-network services so you can get the care you need from home. To get started, complete our free online assessment to get matched with a psychiatrist. FAQs How are Lexapro and Cymbalta similar? Both Lexapro and Cymbalta make more serotonin available in the brain, which can lead to reduced anxiety and depression symptoms. Both medications are commonly prescribed and FDA-approved for treating generalized anxiety disorder and major depressive disorder. How are they different? Lexapro is a selective serotonin reuptake inhibitor (SSRI), and Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI). This means that Lexapro targets only serotonin, whereas Cymbalta targets both serotonin and norepinephrine. Cymbalta also has more FDA-approved indications, such as for pain-related disorders (chronic musculoskeletal pain, fibromyalgia, and diabetic peripheral neuropathic pain). Which one should I take? Your psychiatrist will determine whether Lexapro or Cymbalta is a better fit for you based on your symptoms, diagnoses, co-occurring health conditions, tolerance of medications, and more. If you start out with one and don’t experience the results you hoped for, you can always try the other, as long as your psychiatrist thinks it’s safe for you. What are other alternatives to Lexapro and Cymbalta? There are various other SSRI and SNRI options aApart from Lexapro and Cymbalta. Other SSRIs are: Celexa (citalopram) Prozac (fluoxetine) Luvox (fluvoxamine) Paxil (paroxetine) Zoloft (sertraline) Other SNRIs are: Effexor (venlafaxine) Fetzima (levomilnacipran) Pristiq desvenlafaxine Additionally, there are other classes of antidepressants that your doctor can prescribe if SSRIs or SSRIs aren’t the right
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