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Author: Admin | 2025-04-28
Escitalopram (Lexapro) and sertraline (Zoloft) are two commonly prescribed medications for mental health conditions like depression. They are both similar, but one may better suit your needs.Lexapro and Zoloft are brand names for two antidepressants that are part of the drug class called selective serotonin reuptake inhibitors (SSRIs). They work by increasing levels of serotonin — a substance in the brain that helps with your mood. Both of these medications may work well for you, but there are some similarities and differences between the two.What conditions do they treat?Edward Córdoba/Andréas Sichel/Stocksy UnitedDoctors use escitalopram (Lexapro) to treat depression and generalized anxiety disorder (GAD). They may use sertraline (Zoloft) to treat depression, obsessive-compulsive disorder (OCD), and several other mental health conditions. The table below shows which condition the Food and Drug Administration (FDA) approves each drug for.Key comparisons of Lexapro and ZoloftThe table below compares other key aspects of Lexapro and Zoloft.If you’ve been taking either drug for longer than a few weeks, you should not stop taking it without talking with a doctor, as you’ll need to taper off slowly to avoid withdrawal symptoms.Need a refill for escitalopram oxalate (Lexapro) or sertraline (Zoloft)? You may be able to get an online prescription through Optum Perks in as little as 15 minutes with no video or appointment needed. Learn more here.100% online careTreatment plans in 15 minutes or less for 40+ conditions.Start consult nowWhat do the drugs cost?Both medications are available in most pharmacies in both brand-name and generic versions. Generic options are typically more cost-effective than brand-name products. Lexapro and Zoloft are similar in price, although the costs can fluctuate. You can check current Optum Perks prices by searching for each drug here.Health insurance plans typically cover antidepressant medications such as Lexapro and Zoloft, but they may prefer you to use the generic versions. You can check your drug formulary, also called a drug list, to see which comes under your plan.Side effectsAs Lexapro and Zoloft are both SSRIs, they share many of the same side effects.The table below lists some of the more common side effects you may experience
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