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Author: Admin | 2025-04-28
Key TakeawaysYou can take Zofran up to 3 times a day for 1-2 days after completing your cancer treatment until it is no longer needed. If you are experiencing nausea and vomiting after surgery or cancer treatment such as chemotherapy and radiation treatment, your doctor may prescribe a medication called ondansetron (brand name: Zofran). You can take Zofran up to 3 times a day for 1-2 days after completing your cancer treatment until it is no longer needed. Make sure to adhere to the Zofran schedule prescribed by your doctor and take this medication regularly to get maximum benefits. Please continue reading to learn more about Zofran, including its uses, dosage, and frequency of use. We will also talk about how it works for the prevention of nausea and vomiting, whether it is safe to use during pregnancy, potential drug interactions, and tips on safe Zofran use. What is ondansetron (Zofran)?Ondansetron (Zofran, Zofran ODT) is a prescription medication used to prevent nausea and vomiting for cancer patients after chemotherapy and radiation treatment. It is also used to treat nausea after surgery. There may be additional uses of ondansetron (Zofran)—your doctor or pharmacist can give you further information.Zofran is available in various dosage forms, including oral tablets (4 mg, 8 mg, and 24 mg), orally disintegrating tablets and oral films (4 mg and 8 mg), an oral solution (4 mg/5 mL), and injection vials (2 mg/mL).Dosage forms such as the orally disintegrating tablet, the oral liquid, and the oral film may cause less of a nauseating feeling than that caused by swallowing a tablet. How does Zofran work?Zofran is an antiemetic that belongs to a group of drugs called 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and initiate a vomiting reflex.What is the usual dose of Zofran?The usual dose of ondansetron (Zofran) in adults and children is as follows:AdultsSevere nausea and vomiting due to chemotherapy: a single 24-mg dose to be taken 30 minutes before the start of a single day of highly emetogenic (vomiting-inducing) chemotherapy. Moderate nausea and vomiting due to chemotherapy: An 8-mg tablet is administered 30 minutes before the start of chemotherapy, followed by another 8-mg dose 8 hours later. After the completion of chemotherapy, 8 mg of Zofran should be taken every 12 hours for 1 to 2 days.Radiation therapy: An 8-mg ondansetron is taken 1-2 hours before radiation therapy. After the first dose, the regimen of 8 mg every 8 hours is recommended depending on the type and the location of radiation.Post-operative (after-surgery) nausea and vomiting: 16 mg of ondansetron is to be administered 1 hour before anesthesia. Children:Age 4 to 11:
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