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Author: Admin | 2025-04-28
Small decrements; use the smallest dose needed for adequate clinical response.Withdraw long-term therapy gradually.Usual Adult Dose for OsteoarthritisInjectable 30 mg/5 mL suspension: 0.5 to 2 mL intraarticular injectionVery large joint (hip): 1 to 2 mLLarge joint (knee, ankle, shoulder): 1 mLMedium joint (elbow, wrist): 0.5 to 1 mLSmall joint (metacarpophalangeal, interphalangeal, sternoclavicular, hand, chest): 0.25 to 0.5 mLComments:Duration of relief varies widely.Intraarticular injection relieves pain, soreness, and stiffness; the injection is usually almost painless.A portion of the dose is systemically absorbed; consider any concomitant oral or parenteral corticosteroids (especially if high dose) in determining the intraarticular dose.Dose requirements are variable; individualize dose based on disease and patient response.When a favorable response is achieved, determine maintenance dose by decreasing the dosage in small decrements; use the smallest dose needed for adequate clinical response.Withdraw long-term therapy gradually.Uses: Adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in acute gouty arthritis; acute rheumatic carditis; ankylosing spondylitis; psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy).Usual Adult Dose for Rheumatoid ArthritisInjectable 30 mg/5 mL suspension: 0.5 to 2 mL intraarticular injectionVery large joint (hip): 1 to 2 mLLarge joint (knee, ankle, shoulder): 1 mLMedium joint (elbow, wrist): 0.5 to 1 mLSmall joint (metacarpophalangeal, interphalangeal, sternoclavicular, hand, chest): 0.25 to 0.5 mLComments:Duration of relief varies widely.Intraarticular injection relieves pain, soreness, and stiffness; the injection is usually almost painless.A portion of the dose is systemically absorbed; consider any concomitant oral or parenteral corticosteroids (especially if high dose) in determining the intraarticular dose.Dose requirements are variable; individualize dose based on disease and patient response.When a favorable response is achieved, determine maintenance dose by decreasing the dosage in small decrements; use the smallest dose needed for adequate clinical response.Withdraw long-term therapy gradually.Uses: Adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in acute gouty arthritis; acute rheumatic carditis; ankylosing spondylitis; psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy).Usual Pediatric Dose for Anti-inflammatoryInjectable 30 mg/5 mL suspension:Initial dose: 0.02 to 0.3 mg/kg/day intramuscularly in 3 or 4 divided dosesComments:Dose requirements are variable; individualize dose based on disease and patient response.When a favorable response is achieved, determine maintenance dose by decreasing the dosage in small decrements; use the smallest dose needed for adequate clinical response.Withdraw long-term therapy gradually.Benzyl alcohol preservative is associated with fatal "Gasping Syndrome" in premature and low birth weight infants; use preservative free formulations for neonates, especially premature infants.Renal Dose AdjustmentsUse with caution.Liver Dose AdjustmentsData not availableDose AdjustmentsDose adjustments may be needed for changes in clinical status due to remission or exacerbation of the disease, individual drug responsiveness, and exposure to stress.PrecautionsCONTRAINDICATIONS:Hypersensitivity to any of the ingredientsIntramuscular formulations are contraindicated in idiopathic thrombocytopenic purpuraAdministration of live vaccines is contraindicated in patients on immunosuppressive doses of corticosteroidsConsult WARNINGS section for additional precautions.DialysisData not availableOther CommentsIV compatibility:May combine with 1% or 2% lidocaine hydrochloride (non-parabens formulations) for local anesthesia; add lidocaine into the betamethasone
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