Statin drugs and liver function

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Author: Admin | 2025-04-28

Of blood flow. Evidence suggests that by reducing LDL, statins can improve the endothelial function of penile arteries and, in turn, improve erections in some people. Statins may also increase the nitric oxide levels in the bloodstream. Nitric oxide is a molecule that helps trigger an erection by relaxing penile tissues, allowing blood to flow in and engorge the penis. This is not to suggest that statins have the same level of action as drugs like Viagra or Cialis, which also increases nitric oxide levels. But they may contribute to improved erections in some people.StudyA 2014 review of studies in the Journal of Sexual Medicine concluded that statins improve erectile function in men with high cholesterol and ED by roughly 24%. This effect was seen irrespective of age or a person's LDL level. Statins and Testosterone Like all drugs, statins have side effects. These include muscle pain, diabetes, liver toxicity, and memory loss or confusion. These side effects are more likely in older adults who take multiple drugs or have liver or kidney disease. A lesser-known side effect is reduced testosterone levels. Testosterone is a hormone that regulates muscle growth, bone mass, and libido (sex drive). It also influences erections. However, the reduction of testosterone may not be clinically significant and therefore may not affect sexual function. Testosterone modulates many components of erectile function, including nerves and muscles. It also regulates sexual desire, coordinating erection with sexual intercourse timing. Loss of libido may affect erections by dampening sexual arousal. On the other hand, low testosterone is thought to decrease nitric oxide levels and, in turn, reduce blood flow to the penis.There is some evidence that testosterone replacement therapy can be helpful for people with mild ED, though it may be less helpful for people with more severe ED. At present, it is hard to tell whether a drop in testosterone in statin users is enough to influence erections. The evidence suggests that the average change is small and may not be clinically significant. By contrast, the benefits of statins in people at risk of heart disease almost invariably outweigh the risks. Statins and ED Drugs Generally speaking, it is OK to take ED drugs like Viagra or Cialis while on statin therapy. There are no known interactions, but this doesn't mean that everyone on statin drugs can take them. Viagra (sildenafil) and Cialis (tadalafil) belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which also include Levitra (vardenafil), Stanyx (vardenafil dissolvable), and Stendra (avanafil). PDE5 inhibitors work by causing blood vessels to dilate, increasing the flow of blood to the penis. For some people with heart disease, this action can cause adverse and potentially dangerous effects.WarningPDE5 inhibitors

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