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Author: Admin | 2025-04-28
ED treatment guidelines from experts at the American Urological Association. In fact, the FDA denied approval of apomorphine for ED in 2003. We also know that apomorphine doesn’t work as well as phosphodiesterase type 5 (PDE5) inhibitors for ED. A 2008 study found that sildenafil (brand name Viagra)—a type of PDE5 inhibitor—works better than sublingual apomorphine for getting an erection and feeling satisfied. Still, sublingual apomorphine could be worth considering for individuals with mild-to-moderate psychogenic ED who can’t take PDE5 inhibitors due to contraindications, such as nitrate use. Then again, as explained above, sublingual apomorphine isn’t available in the US. So, what about apomorphine injections for ED? Do those work for treating the condition? Unfortunately, there is little-to-no research on apomorphine injections for ED. Only the sublingual form of the drug has been studied for ED. Is apomorphine for ED safe? Apomorphine injections may cause various side effects, including nausea, vomiting, constipation, headache, yawning, and weakness. Serious side effects can include prolonged painful erections (priapism), rash, difficulty breathing, fainting, fast heartbeat, hallucinations, depression, and chest pain. The drug labeling also includes safety warnings for potential drowsiness and falling asleep during daily activities as well as problems with impulsive behaviors. And older adults (65+) are more likely to experience certain side effects than younger adults. Keep in mind that side effect data for apomorphine injections is based on its use (and dosage) for PD. Again, this formulation of the drug has not been studied as a treatment for ED. Sublingual apomorphine gets mixed reviews for safety. Some clinical research suggests that sublingual apomorphine may be easier to tolerate, with reports of mild nausea that eases with continued use. (But, as mentioned, sublingual apomorphine isn’t available in the US. It was also discontinued in Canada for business reasons.)Apomorphine likely isn’t a safe
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