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Author: Admin | 2025-04-28
Lexapro vs. Wellbutrin: Which more effective? Lexapro and Wellbutrin are two different antidepressants, which are both effective at treating depression and can also be taken together.If you’re considering medication for the treatment of depression or another mental health condition, you may have come across the two brand names Lexapro and Wellbutrin. Both are very commonly prescribed antidepressants, but each works in a different way. Navigating the maze of antidepressant options can feel overwhelming, which is why we’ve put together a guide comparing these two medications. In this deep dive, we'll compare Lexapro and Wellbutrin, exploring how each actually works, what conditions they are best suited to treat, their side effects, and more. By the end, you’ll be equipped to have an informed conversation with your doctor about these two drugs. Expert care for anxiety is here. See if Talkiatry is right for you.Start our short assessmentWhat conditions do they treat? Lexapro (escitalopram), is FDA-approved for treating major depressive disorder (MDD) and generalized anxiety disorder (GAD). Additionally, it's often prescribed off-label for conditions like social anxiety disorder, obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and post-traumatic stress disorder (PTSD). Wellbutrin (bupropion) is FDA-approved for MDD, seasonal affective disorder (SAD), and smoking cessation. It's also prescribed off-label for anxiety and attention-deficit/hyperactivity disorder (ADHD), among other conditions. Related article: How to get depression medication How do they work? Although both Lexapro and Wellbutrin are antidepressants, they are different classes of prescription drugs with distinct mechanisms of action. Lexapro is a selective serotonin reuptake inhibitor, or SSRI, a drug class that is commonly used to treat depression and anxiety. Serotonin is a chemical messenger, or neurotransmitter, that helps transfer information between nerve cells, and it’s known to be connected to our mood and emotions. SSRIs work by preventing your nerve cells
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