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Author: Admin | 2025-04-28
Is meant to be used in addition to diet and exercise. (For more information, see the “Mounjaro use with other treatments” section.)Mounjaro has two limitations of use:The drug is not approved for use in people with type 1 diabetes. Based on how Mounjaro works, it would likely be ineffective in managing this condition.Mounjaro may not be safe for you if you have or have had pancreatitis (inflammation of the pancreas).Note: Mounjaro may also be prescribed off-label for other conditions. Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what it’s approved for.Type 2 diabetes explainedWhen you eat, your body naturally makes hormones called incretins. These hormones signal your pancreas to release insulin and also help you feel full. Incretins help keep your blood sugar within a range that’s healthy for you. This process is called the incretin effect.Type 2 diabetes diminishes the incretin effect. This leads to hyperglycemia (high blood sugar). Over time, having too much sugar in your blood can cause complications of diabetes. These may include damage to your nerves, eyes, kidneys, and certain tissues. High blood sugar can also increase your risk of cardiovascular problems, such as a heart attack or stroke.Possible symptoms of type 2 diabetes can include:weight lossfatigueextreme thirsturinating more often than usualblurry visionYou can learn more about diabetes by visiting our diabetes hub.Effectiveness for type 2 diabetesTirzepatide (the active ingredient in Mounjaro) has been shown to be effective in managing blood sugar levels in adults with type 2 diabetes.You can read about how the drug performed in clinical trials.Mounjaro and childrenMounjaro is for use only in adults with type 2 diabetes. The drug is not approved for use in children.Mounjaro is used to help manage blood sugar levels in adults with type 2 diabetes. With this condition, the body doesn’t respond to insulin in the typical way. (Insulin is a type of hormone that helps move sugar from the blood into cells. The cells use insulin as energy.) Eventually, an organ called the pancreas creates less insulin.Mounjaro is a type of drug called a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Mounjaro is the first medication in the GIP/GLP-1 receptor agonist drug class.What Mounjaro doesMounjaro’s mechanism of action (how it works in the body) is to imitate the effects of hormones called incretins. Specifically, Mounjaro mimics incretins known as GIP and GLP-1 by activating certain receptors (binding sites) in the body.By activating these receptors, Mounjaro lowers fasting and post-meal blood sugar levels. The drug does this by:signaling your pancreas to release more insulin after you eatmaking your body extra sensitive to insulinstopping your liver from making additional sugarMounjaro also slows the movement of food through your digestive tract, which can make you feel full for longer than usual.When used along with a nutritious diet and regular exercise, Mounjaro may help manage your blood sugar level. (For more about the drug’s use with diet and exercise, see the “Mounjaro use with other treatments” section.)How long
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