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Author: Admin | 2025-04-28
UsageOxycodone is used to treat chronic moderate to severe pain, as well as managing breakthrough or acute excessive pain in patients who are treated for chronic pain. OxyContin has similar pain-killing effects but it's used to treat chronic pain. OxyContin is not effective for immediate pain relief (for example in an emergency room).DosageThe initial adult dose of oxycodone is 5mg to 15mg taken orally every 4 to 6 hours. This can be increased up to 30mg every 4 hours.Children who weigh over 50kg can take 5mg of oxycodone every 6 hours, which may be raised to 10mg every 3 to 4 hours over time. OxyContin is only available in time-release form. Its initial dosage is 10mg every 12 hours, increasing to up to 640mg per day in patients with cancer pain. The average daily dose is 105mg per day.Which is Stronger - OxyContin or Oxycodone?This is a bit of a trick question because the active ingredient in OxyContin is oxycodone. However, oxycodone immediate release (IR) will by definition be "stronger" than a continuous release (CR) formulation that is absorbed over a period of time.WarningsOxycodone and OxyContin should not be combined with alcohol, as this can lead to death. It should also not be combined with sedatives, tranquilizers, sleeping pills or muscle relaxers.EfficacyA study by the NCBI suggests that oxycodone and OxyContin are equally effective in treating moderate to severe chronic back pain. Specifically, the study concluded thatControlled-release oxycodone given every 12 hours was comparable with immediate-release oxycodone given four times daily in efficacy and safety, and it provides convenient, twice-daily, around-the-clock treatment for selected patients with persistent back pain that is inadequately controlled by nonopioids or as-needed opioid therapy.Other studies have focused on cancer-related pain and reached the same conclusion — immediate-release oxycodone is as effective as controlled-release OxyContin. A 2001 study echoed what a prior study in 1998 concluded: CR oxycodone [i.e., OxyContin] every 12 hours was as effective as IR oxycodone four times daily in managing moderate to severe cancer-related pain and was associated with fewer reports of adverse events.How long does OxyContin's pain relief last?When Purdue launched OxyContin, the pharmaceutical company made the claim that one dose of OxyContin relieves pain for 12 hours, which is roughly twice as long as generic medications. But an LA Times investigation found that the claim is misleading and false because drug wears off early for many people. To combat this phenomenon of the drug wearing off earlier, doctors can either increase the frequency or the dosage of the drug. The LA Times alleged in its reporting that Purdue tells doctors to prescribe stronger doses, not more frequent ones, when patients complain that OxyContin doesn’t last 12 hours. That approach creates
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